CCNA Team 3: Protein Misfolding in Neurodegeneration

“One commonality among [Parkinson’s, Frontotemporal dementia, ALS and Alzheimer’s disease] is neuron death. The location of neuron death determines the disease type. Another commonality is protein deposits in dying neurons. … The Chakrabartty Lab has created a tool called STOP, which we can use to identify important components of neurodegenerative diseases and we can then use to target potential therapies.”