{"id":4678,"date":"2020-12-17T14:16:47","date_gmt":"2020-12-17T19:16:47","guid":{"rendered":"https:\/\/ccna-ccnv.ca\/ccna_publication\/neural-correlates-of-resilience-to-the-effects-of-hippocampal-atrophy-on-memory-2\/"},"modified":"2024-12-03T14:57:21","modified_gmt":"2024-12-03T19:57:21","slug":"neural-correlates-of-resilience-to-the-effects-of-hippocampal-atrophy-on-memory-2","status":"publish","type":"ccna_publication","link":"https:\/\/ccna-ccnv.ca\/fr\/ccna_publication\/neural-correlates-of-resilience-to-the-effects-of-hippocampal-atrophy-on-memory-2\/","title":{"rendered":"Neural correlates of resilience to the effects of hippocampal atrophy on memory"},"content":{"rendered":"<h2 class=\"section-title u-h3 u-margin-l-top u-margin-xs-bottom\">Abstract<\/h2>\n<div id=\"as010\">\n<h3 id=\"st015\" class=\"u-h4 u-margin-m-top u-margin-xs-bottom\">Introduction<\/h3>\n<p id=\"sp0010\">Cognitive reserve can be defined as a property of the brain that enables an individual to sustain cognitive performance in spite of age-related neural changes. This study uses brain imaging to identify which cognitive reserve mechanisms protect against the detrimental effect of hippocampal atrophy on associative memory.<\/p>\n<\/div>\n<div id=\"as015\">\n<h3 id=\"st020\" class=\"u-h4 u-margin-m-top u-margin-xs-bottom\">Methods<\/h3>\n<p id=\"sp0015\">The study included 108 older adults from the Quebec Consortium for the early identification of Alzheimer\u2019s disease. They received a magnetic resonance imaging examination to measure memory-related activations and hippocampal volume. Participants also completed a reserve-proxy questionnaire, and received a comprehensive clinical assessment.<\/p>\n<\/div>\n<div id=\"as020\">\n<h3 id=\"st025\" class=\"u-h4 u-margin-m-top u-margin-xs-bottom\">Results<\/h3>\n<p id=\"sp0020\">Higher scores on the reserve questionnaire were associated with more activation in the right inferior temporal and left occipital fusiform gyri. The activation of the right temporal gyrus moderated the relationship between the volume of the hippocampus and face-name memory. A smaller volume was associated with weaker memory in participants with lower activation, but not in those with greater activation.<\/p>\n<\/div>\n<div id=\"as025\">\n<h3 id=\"st030\" class=\"u-h4 u-margin-m-top u-margin-xs-bottom\">Discussion<\/h3>\n<p id=\"sp0025\">Recruitment of the temporal lobe protects against the detrimental effect of hippocampal atrophy on associative memory and contributes to cognitive reserve.<\/p>\n<\/div>\n","protected":false},"author":19,"featured_media":0,"template":"","meta":{"_acf_changed":false},"studies-relation":[],"class_list":["post-4678","ccna_publication","type-ccna_publication","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Neural correlates of resilience to the effects of hippocampal atrophy on memory - CCNA - CCNV<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ccna-ccnv.ca\/fr\/ccna_publication\/neural-correlates-of-resilience-to-the-effects-of-hippocampal-atrophy-on-memory-2\/\" \/>\n<meta property=\"og:locale\" content=\"fr_CA\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Neural correlates of resilience to the effects of hippocampal atrophy on memory - 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