{"id":4817,"date":"2021-05-25T20:04:22","date_gmt":"2021-05-26T00:04:22","guid":{"rendered":"https:\/\/ccna-ccnv.ca\/ccna_publication\/white-matter-degeneration-a-treatable-target-2\/"},"modified":"2024-12-03T14:57:44","modified_gmt":"2024-12-03T19:57:44","slug":"white-matter-degeneration-a-treatable-target-2","status":"publish","type":"ccna_publication","link":"https:\/\/ccna-ccnv.ca\/fr\/ccna_publication\/white-matter-degeneration-a-treatable-target-2\/","title":{"rendered":"White matter degeneration \u2013 a treatable target?"},"content":{"rendered":"<div class=\"widget-ArticleFulltext widget-instance-AMA_Article_Abstract_Widget\">\n<div class=\"article-full-text\" data-userhasaccess=\"False\">\n<p class=\"para\">The World Health Organization predicts that by 2050, one-fifth of the world\u2019s population will be older than 60 years, with roughly 115 million individuals affected by dementia.\u00a0These numbers do not account for the additional 16% to 20% of elderly individuals who are estimated to experience mild cognitive impairment, which can begin years before clinical presentation.\u00a0Despite this large public health concern, interventional strategies are limited, and timely identification of prodromal disease states requires improvement. To date, most therapies aim to protect or preserve at-risk neurons, and there are very few therapies that target the brain\u2019s white matter, which makes up half of the brain and may be a critical site of prodromal disease.<\/p>\n<div class=\"movable-ad-target bta\"><\/div>\n<\/div>\n<\/div>\n<div class=\"widget-ArticleLinks widget-instance-AMA_Abstract_EditorialComments\"><\/div>\n<p><a class=\"full-text-link is-b d-b bd-none ta-c fl-n radius mt1 mb1 m-auto\" data-url=\"\" data-article-id=\"2764333\">\u00a0<\/a><\/p>\n","protected":false},"author":19,"featured_media":0,"template":"","meta":{"_acf_changed":false},"studies-relation":[],"class_list":["post-4817","ccna_publication","type-ccna_publication","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.8 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>White matter degeneration \u2013 a treatable target? - CCNA - CCNV<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ccna-ccnv.ca\/fr\/ccna_publication\/white-matter-degeneration-a-treatable-target-2\/\" \/>\n<meta property=\"og:locale\" content=\"fr_CA\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"White matter degeneration \u2013 a treatable target? 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