The Largest Canadian Study on Dementia, COMPASS-ND, nears 50% Recruitment

By the end of May 2020, 1650 Canadians between the ages of 50 and 90 who are living with, or are at risk of developing, dementia will be enrolled in 30 sites across Canada.

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Who we are

The Canadian Consortium on Neurodegeneration in Aging (CCNA) provides the infrastructure and support that facilitates collaboration amongst Canada’s top dementia researchers. By accelerating the discovery, innovation, and the adoption of new knowledge, the CCNA positions Canada as a global leader in increasing understanding of neurodegenerative diseases, working towards prevention, and improving the quality of life of those living with dementia.

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News

Discovery by CCNA Researchers: Markers of Alzheimer’s disease and Mild Cognitive Impairment Found in Human Saliva

Researchers within the Canadian Consortium on Neurodegeneration in Aging (CCNA) have identified markers in human saliva that indicate the presence of Alzheimer’s disease (AD) and mild cognitive impairment (MCI). Drs. Roger Dixon and Liang Li specialize in biomarker research in aging and dementia. In other words, they work with people who are aging to identify whether there are substances in their bodies that indicate the presence of a specific disease or infection. For this study, they worked with three groups of patients – who are living with AD, MCI, or have unimpaired cognition. To identify markers of the diseases or changes over time, Dixon and Li examined 6000+ metabolites (which are substances that are formed in, or necessary for, metabolism). They did this using a mass spectrometer, which is an apparatus that separates isotopes, molecules, and molecular fragments based on their mass. Their discovery – of three biomarkers that can detect AD and MCI – may lead to the development of a saliva test that can diagnose the diseases in the future.

Parkinson’s disease: new research on the role of cognition and sex differences

This guest blog was written by CCNA researchers Ashley Curtis, Mario Masellis, Richard Camicioli, Heather Davidson, and Mary Tierney Parkinson’s disease (PD) mainly affects the body’s motor system. It's symptoms – which result from the long-term degeneration of the central nervous system – occur over time and include shaking, difficulty walking, slow movements, and rigidity….

New Fund to Help Support People Living with Dementia

“Through our consultations, we heard from stakeholders, people living with dementia, as well as their family or friend caregivers. Many expressed a need for collaboration and partnership, information sharing, scaling up of best practices, and measures that address stigma. I am confident that through the Dementia Community Investment fund, we can learn more and implement effective approaches to supporting optimal quality of life for those living with dementia and their family or friend caregivers.”

The Honourable Ginette Petitpas Taylor
Minister of Health Canada

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