CCNA’s research in Phase II aims to strengthen the understanding of:
- How neurodegenerative diseases develop
- Ways of slowing Dementia progression and eventually preventing it altogether
- Dementia’s impact on the individual, families, and the community as a whole
See our Phase II- year 2 accomplishments in a few numbers:
And how about looking at Phase II – year 1 numbers!
CCNA’s research is organized into three Themes:
- Theme 1: Prevention
- Team 1 – Clinical Genetics and Gene Discovery/ Leads: Ekaterina Rogaeva and Ziv Gan-Or
- Team 2 – Inflammation & Nerve Growth Factors / Leads: Claudio Cuello, Margaret Fahnestock, and Pedro Rosa-Neto
- Team 3 – Protein Misfolding / Lead: Neil Cashman
- Team 4 – Early Detection and Prevention of Neurodegenerative Diseases / Lead: Robert Bartha
- Team 5 – Nutrition, Exercise, and Lifestyle in Alzheimer’s Disease Prevention / Lead: Guylaine Ferland
- Theme 2: Treatment
- Team 6 – Sleep and Dementia / Leads: Julie Carrier and Andrew Lim
- Team 7 – Vascular Illness and its Impact on Neurodegenerative Diseases / Leads: Eric E. Smith and Bojana Stefanovic
- Team 8 – Lewy Bodies, Aging, and Dementia / Lead: Richard Camicioli
- Team 9 – Developing New Biomarkers / Leads: Roger A. Dixon and Pierre Bellec
- Team 10 – Cognitive Intervention, Reserve and Brain Plasticity / Leads: Sylvie Belleville and Nicole Anderson
- Team 11 – Prevention and Treatment of Neuropsychiatric Symptoms / Leads: Nathan Herrmann, Krista Lanctôt, and Dallas Seitz
- Team 12 – Mobility, Exercise, and Cognition / Leads: Manuel Montero-Odasso and Louis Bherer
- Team 13 – Frontotemporal Dementia / Leads: Elizabeth Finger and Simon Ducharme
- Theme 3: Quality of Life
- Team 14 – Multi-Morbidity and Dementia / Lead: Kenneth Rockwood
- Team 15 – Issues in Dementia Care for Rural populations / Lead: Megan O’Connell
- Team 16 – Driving & Dementia / Leads: Gary Naglie and Mark Rapoport
- Team 17 – Interventions at the Sensory and Cognitive Interface / Leads: Natalie Phillips and Walter Wittich
- Team 18 – Issues in Dementia Care for Indigenous Populations / Lead: Jennifer Walker
- Team 19 – Integrating Dementia Patient Care into the Health Care System / Leads: Isabelle Vedel and Howard Bergman
CCNA’s signature study, involving all three Themes, is The Comprehensive Assessment of Neurodegeneration and Dementia (COMPASS-ND). It is a large scale clinical study aiming to understand dementia risk factors and tests of early detection of dementia. Interested participants may contact us here: ccna.admin@ladydavis.ca.
Seven national platforms were established to facilitate the research.
This work builds on the research conducted at CCNA in Phase 1.