Lead: Gillian Einstein
Program Manager: Lindsey Thurston
Our goal is to work with CCNA’s research teams to ensure that relevant sex and gender research questions will be studied across the spectrum of neurodegeneration in both human and animal model studies.
By amplifying the focus on sex and gender, CCNA’s research teams can capture important sex and gender differences in the prevalence, incidence, symptoms, and progression of neurodegenerative diseases. For example, these differences may be due to biological and physiological variations between the sexes, and/or gender differences in roles, occupations, environmental exposures, and other life experiences. Understanding sex and gender differences and how they interact is critical for developing interventions for both the prevention and treatment of neurodegeneration.
Objectives
Creating guidelines to ensure that the data collected in the COMPASS-ND study, a clinical cohort study, will enable teams to examine sex and gender differences in the 1600 cohort participants.
Ensuring that each sex will be equally represented in all of the neurodegenerative conditions within the clinical cohort.
Working with the teams using animal models to support the inclusion of both male and female experimental animals, to ensure generalizability of the findings to both sexes.
Ensuring that every CCNA publication and presentation reports sex differences in human participants, cell lines, and experimental animals (mandated through the Publications and Data Access Policy).
Grant writing resource:
Publication sample
2025
Authors:
Kumar, R., Calvo, N., & Einstein, G.
Journal:
Frontiers in Global Women's Health
2024
Authors:
Bohn, L.,** Han, A. Y.,** McFall, G. P.,* Drouin, S. M.,* Pettersen, J. A.,* Rajah, M. N.,* Einstein, G.,* Anstey, K. J., & Dixon, R. A.*
Journal:
Innovation in Aging
2024
Authors:
Couture, V., Carmel, J. F., Rousseau, K., Létourneau, G., Clerc, D., Huot, P., Forget, M. F., Nguyen, Q. D., Camicioli, R., & Desmarais, P.
Journal:
Movement Disorders Clinical Practice
2024
Authors:
Calvo, N., McFall, G. P., Ramana, S., Galper, M., Fuller-Thomson, E., Dixon, R. A., & Einstein, G.
Journal:
Journal of Alzheimer's Disease
2024
Authors:
Lissaman, R., Rajagopal, S., Kearley, J., Pasvanis, S., & Rajah, M. N.
Journal:
Neurobiology of Aging
2024
Authors:
Frame, A. K., Sinka, J. L., Courchesne, M., Muhammad, R. A., Grahovac-Nemeth, S., Bernards, M. A., Bartha, R., & Cumming, R. C.
Journal:
iScience
2024
Authors:
Duval, A., Beatty-Martínez, A. L., Pasvanis, S., Crestol, A., Snytte, J., Rajah, M. N., & Titone, D. A
Journal:
Journal of Experimental Psychology
2024
Authors:
Kapustin, D., Tumati, S.**, Wong, M., Herrmann, N.*, Dixon, R.A.*, Seitz, D.*, Rapoport, M.J.*, & Lanctôt, K.L.*
Journal:
International Journal of Geriatric Psychiatry
2024
Authors:
Arsenault-Lapierre, G., Bui, T., Godard-Sebillotte, C., Kang, N., Sourial, N., Rochette, L., Massamba, V., Quesnel-Vallée, A., & Vedel, I.
Journal:
Journal of Aging and Health
2024
Authors:
Subramaniapillai, S., Am Galea, L., Einstein, G., & de Lange, A. M.
Journal:
Frontiers in Neuroendocrinology
2024
Authors:
L. K Fitzgibbon-Collins, G. B. Coombs, M. Noguchi, S.j Parihar, R. L. Hughson, M. Borrie, S. Peters, J. K. Shoemaker, J. Bhangu
Journal:
Cerebral Circulation - Cognition and Behavior
2023
Authors:
Crestol, A., Rajagopal, S., Lissaman, R., LaPlume, A. A., Pasvanis, S., Olsen, R. K., Einstein, G., Jacobs, E. G., & Rajah, M. N.
Journal:
The Journal of Neuroscience
2023
Authors:
Perović, M., Heffernan, E. M., Einstein, G., & Mack, M. L.
Journal:
Scientific Reports
2023
Authors:
Crestol, A., Rajagopal, S., Lissaman, R., LaPlume, A. A., Pasvanis, S., Olsen, R. K., Einstein, G., Jacobs, E. G., & Rajah, M. N.
Journal:
The Journal of Neuroscience
2023
Authors:
Calvo, N., & Einstein, G.
Journal:
Frontiers in Aging Neuroscience
2022
Authors:
Al-Yawer, F.**, Pichora-Fuller, M. K.*, Wittich, W.*, Mick, P.*, Giroud, N., Rehan, S.**, & Phillips, N. A.*
Journal:
Ear and Hearing
2022
Authors:
Reavis, K.M., Bisgaard, N., Canlon, B., Dubno, J.R., Frisina, R.D., Hertzano, R., Humes, L.E., Mick, P.*, Phillips, N.A.*, Pichora-Fuller, M.K*., Shuster , B., & Singh, G.
Journal:
Ear and Hearing
2022
Authors:
Heal, M.**, McFall, G. P.*, Vergote, D., Jhamandas, J. H.*, Westaway, D.*, & Dixon, R. A.*
Journal:
Journal of Alzheimer's Disease
2022
Authors:
Duchaine C.S.**, Fiocco A.J*, Carmichael P.H, Cunnane S.C, Plourde M., Lampuré A., Allès B., Belleville S.*, Gaudreau P.*, Presse N.*, Ferland G.*, Laurin D.*
Journal:
Journal of Nutrition
2022
Authors:
D. X. Guan, K. Rockwood, E. E. Smith, Z. Ismail
Journal:
The Journal of Prevention of Alzheimer’s Disease
2021
Authors:
Al-Yawer, F.**, Bruce, H., Li, K., Pichora-Fuller, M. K.*, & Phillips, N. A.*
Journal:
American Journal of Audiology
2020
Authors:
Olson NL, Albensi BC*
Journal:
Journbal of Alzheimer's Disease Reports
2021
Authors:
Wang YTT, Pascoal TA, Therriault J, Kang MS, Benedet AL*, Savard M, Tissot C, Lussier FZ, Arias JF, Mathotaarachchi S, Rajah MN*, Gauthier S* and Rosa-Neto P* for the Alzheimer’s Disease Neuroimaging Initiative
Journal:
Brain Communications
2021
Authors:
Trenaman SC*, Bowles SK, Andrews MK*, Goralski K
Journal:
Pharmacology Research and Perspectives
2020
Authors:
Kozyrev N, Albers S, Yang J, Prado VF*, Prado MAM*, Fonseca GJ, Rylett RJ, Debakan GA*
Journal:
Journal of Neuropathology & Experimental Neurology
2021
Authors:
Anstey KJ, Peters R, Mortby ME, Kiely KM, Eramudugolla R, Cherbuin N, Huque H, Dixon RA*
Journal:
Scientific Reports
2021
Authors:
Subramaniapillai S, Rajagopal S, Snytte J, Otto AR, the PREVENT-AD Research Group, Einstein G*, Rajah MN*
Journal:
NeuroImage: Clinical
2020
Authors:
Subramaniapillai S, Almey A, Rajah MN*, Einstein G*
Journal:
Frontiers in Neuroendocrinology
2020
Authors:
Pentz R, Iulita MF, Mikutra-Cencora M, Ducatenzeiler A, Benett DA, Cuello AC*
Journal:
Neurobiology of Disease
2020
Authors:
Sourial N, Arseneault-Lapierre G, Margo-Dermer E, Henein M, Vedel I*
Journal:
International Journal for Equity in Health
2020
Authors:
Gervais NJ, Au A, Almey A, Duchesne A**, Gravelsins L, Brown A, Reuben R, Baker-Sullivan E, Schwartz DH, Evans K, Bernadini MQ, Eisen A, Meschino WS, Foulkes WD, Hampson E, Einstein G*
Journal:
Neurobiology of Aging
2020
Authors:
D’Amico D, Parrott MD, Greenwood CE, Ferland G*, Gaudreau P*, Belleville S*, Laurin D*, Anderson ND*, Kergoat M**, Morais JA, Presse N*, Fiocco AJ*
Journal:
BMC Nutrition Journal
2020
Authors:
Ursenbach J**, O’Connell ME*, Kirk A*, Morgan D*
Journal:
Health and Quality of Life Outcomes
2020
Authors:
Sourial N, Vedel I**, Godard-Sebillotte, C**, Etches J, Arsenault-Lapierre G**, Bronskill SE**
Journal:
Journal of the American Geriatric Society
2019
Authors:
"McFall, GP.**, Backman, L., Dixon, RA**. "
Journal:
Curr Alzheimer Res
2019
Authors:
"Thibeau, S.*, McFall, GP.**, Camicioli, R.**, Dixon, RA**. "
Journal:
Gerontology
2019
Authors:
Trenaman, S.C., Rideout, M., Andrew, M.K.
Journal:
SAGE Open Medicine
2017
Authors:
Tierney, M. C., Curtis, A. F., Chertkow, H., & Rylett, R. J.
Journal:
Alzheimer's & Dementia
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