October 20, 2026, 12pm-1pm ET
Sleep for resilience: Translational insights from mouse models to human dementia with Brianne Kent
Sleep disturbance is a common symptom of Alzheimer’s disease (AD) and reduced slow-wave sleep (SWS) is linked to increased risk of dementia. Our translational work spanning mouse models and human cohorts is evaluating sleep as a modifiable target for promoting resilience to dementia. In a mouse model of AD, chronic administration of the SWS-enhancing antidepressant trazodone reduced markers of AD neuropathology, in addition to consolidating sleep and improving short-term and long-term memory. In humans, we have been studying how sleep is associated with cognitive performance and dementia risk in the Brain Resilience Study, a new open-science initiative integrating sleep, cognition, neuroimaging, and psychosocial data across 1,000+ older adults to advance early, personalized, and equitable dementia prevention.
Please note that registration is required to attend. Click here to register.
Past webinars
What are you looking for?
Communicating about medications and other therapies in a way that is meaningful to people with lived experience of dementia
March 29, 2022
Arts-based knowledge translation: Piece of mind
January 19, 2022
Biomarkers in research and care: Applications and implications
July 21, 2021
Situating the “new dementia” – context and diversity in dementia prevention
April 8, 2021
Researcher-entrepreneurs panel
February 2, 2021
Increasing participant diversity in health research: Literature review and lessons learned from the ENGAGE trial
September 8, 2020
Improbable encounter
August 7, 2020
From 0 to 100 in remote dementia research: A practical guide
July 9, 2020
