October 20, 2026, 12pm-1pm ET
Sleep for resilience: Translational insights from mouse models to human dementia with Brianne Kent
Sleep disturbance is a common symptom of Alzheimer’s disease (AD) and reduced slow-wave sleep (SWS) is linked to increased risk of dementia. Our translational work spanning mouse models and human cohorts is evaluating sleep as a modifiable target for promoting resilience to dementia. In a mouse model of AD, chronic administration of the SWS-enhancing antidepressant trazodone reduced markers of AD neuropathology, in addition to consolidating sleep and improving short-term and long-term memory. In humans, we have been studying how sleep is associated with cognitive performance and dementia risk in the Brain Resilience Study, a new open-science initiative integrating sleep, cognition, neuroimaging, and psychosocial data across 1,000+ older adults to advance early, personalized, and equitable dementia prevention.
Please note that registration is required to attend. Click here to register.
Past webinars
What are you looking for?
Results of ENGAGE trial and next steps
October 3, 2023
New features and data querying workshop
September 19, 2023
Food for thought: The role of dietary intake and nutrition risk in cognitive health among older adults
September 5, 2023
Creative connections: The CCNA training program in phase II
June 27, 2023
The impact of Canada’s pivotal work in dementia diagnosis and care in primary care settings – Will governments and specialist clinicians engage?
June 13, 2023
Amyloid clearance by amyloidolytic activity
May 30, 2023
Selective immunotherapies for Alzheimer’s disease and synucleinopathies
April 25, 2023
An honest conversation on building meaningful engagement with diverse communities in dementia research
March 23, 2023
Understanding stigma against dementia during COVID-19: Lived Experience and Social Media Research
January 18, 2023
Cohesion, At-homeness, and Playfulness (CAP): A place-based model to prevent cognitive decline in the community
November 30, 2022
Staging Alzheimer’s disease in vivo
August 15, 2022
Indigenous engagement and data governance in practice
May 26, 2022
Open access learning resources:
Good Data (2019)
The State of Open Data (2019)
Indigenous Data Sovereignty (2016)
